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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PDSS1 All Species: 10.3
Human Site: T81 Identified Species: 16.19
UniProt: Q5T2R2 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0.21
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q5T2R2 NP_055132.2 415 46261 T81 I S R F H H T T P D S K T H S
Chimpanzee Pan troglodytes XP_507706 415 46302 T81 I S R F H H T T P D S K T H S
Rhesus Macaque Macaca mulatta XP_001102166 415 46267 T81 I S R F H H T T P D S K T H S
Dog Lupus familis XP_849908 365 40815 D59 D L N G L Y E D I R K E L L I
Cat Felis silvestris
Mouse Mus musculus Q33DR2 409 45876 Q79 P A M C S C R Q T Q S G E K Y
Rat Rattus norvegicus Q5U2R1 401 44276 V81 L S D E L S N V A M Q V R K L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506831 398 43655 P78 S G E K Y T D P F K L G R R D
Chicken Gallus gallus XP_418592 366 41291 D60 D L K N L Y E D I K K E L L V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001017656 411 45908 D85 V S C S L H S D A K L K D P F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_733425 436 48954 T99 R Q H S S V H T Q Q P A G P V
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans NP_491588 393 42985 M78 V T S N L G R M T H Y Y F Q Q
Sea Urchin Strong. purpuratus XP_781598 300 33712
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P34802 371 40156 N65 S V V T K E D N L R Q S E P S
Baker's Yeast Sacchar. cerevisiae P18900 473 52541 L92 K V R P L L V L L L S R A L S
Red Bread Mold Neurospora crassa Q7S565 449 48454 T95 A G E M K F L T G N I R K L L
Conservation
Percent
Protein Identity: 100 97.3 96.8 80.4 N.A. 82.8 21.4 N.A. 77.1 71.5 N.A. 62.1 N.A. 46.5 N.A. 35.6 42.8
Protein Similarity: 100 98.5 97.3 84.3 N.A. 87.9 40.2 N.A. 85 80.2 N.A. 76.6 N.A. 65.3 N.A. 54.9 59.5
P-Site Identity: 100 100 100 0 N.A. 6.6 6.6 N.A. 0 0 N.A. 20 N.A. 6.6 N.A. 0 0
P-Site Similarity: 100 100 100 13.3 N.A. 13.3 13.3 N.A. 6.6 20 N.A. 33.3 N.A. 6.6 N.A. 13.3 0
Percent
Protein Identity: N.A. N.A. N.A. 21.4 27 35.8
Protein Similarity: N.A. N.A. N.A. 38 43.5 52.7
P-Site Identity: N.A. N.A. N.A. 6.6 20 6.6
P-Site Similarity: N.A. N.A. N.A. 6.6 26.6 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 7 0 0 0 0 0 0 14 0 0 7 7 0 0 % A
% Cys: 0 0 7 7 0 7 0 0 0 0 0 0 0 0 0 % C
% Asp: 14 0 7 0 0 0 14 20 0 20 0 0 7 0 7 % D
% Glu: 0 0 14 7 0 7 14 0 0 0 0 14 14 0 0 % E
% Phe: 0 0 0 20 0 7 0 0 7 0 0 0 7 0 7 % F
% Gly: 0 14 0 7 0 7 0 0 7 0 0 14 7 0 0 % G
% His: 0 0 7 0 20 27 7 0 0 7 0 0 0 20 0 % H
% Ile: 20 0 0 0 0 0 0 0 14 0 7 0 0 0 7 % I
% Lys: 7 0 7 7 14 0 0 0 0 20 14 27 7 14 0 % K
% Leu: 7 14 0 0 40 7 7 7 14 7 14 0 14 27 14 % L
% Met: 0 0 7 7 0 0 0 7 0 7 0 0 0 0 0 % M
% Asn: 0 0 7 14 0 0 7 7 0 7 0 0 0 0 0 % N
% Pro: 7 0 0 7 0 0 0 7 20 0 7 0 0 20 0 % P
% Gln: 0 7 0 0 0 0 0 7 7 14 14 0 0 7 7 % Q
% Arg: 7 0 27 0 0 0 14 0 0 14 0 14 14 7 0 % R
% Ser: 14 34 7 14 14 7 7 0 0 0 34 7 0 0 34 % S
% Thr: 0 7 0 7 0 7 20 34 14 0 0 0 20 0 0 % T
% Val: 14 14 7 0 0 7 7 7 0 0 0 7 0 0 14 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 7 14 0 0 0 0 7 7 0 0 7 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _